Stochastic Fluctuation-Driven Escape from Extinction: Basics and Application to Virology Full article
| Journal |
Chemical Physics Letters
ISSN: 0009-2614 , E-ISSN: 1873-4448 |
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| Output data | Year: 2025, Volume: 876, Article number : 142168, Pages count : 5 DOI: 10.1016/j.cplett.2025.142168 | ||
| Tags | Extinction and explosion; Intracellular viral kinetics; Model; Monte Carlo simulations | ||
| Authors |
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| Affiliations |
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Funding (1)
| 1 | Ministry of Science and Higher Education of the Russian Federation | FWUR-2024-0032 |
Abstract:
The statistical theory of fluctuation-induced escape from extinction to a stable state or kinetic explosion is of interest in the context of initial infection of cells by virions in order to understand the limits of the applicability of the independent action hypothesis. Herein, the corresponding generic model is scrutinized by using Monte Carlo simulations. The conventional steady-state approximation is shown to overestimate appreciably the escape probability. Then, the infection of individuals inhaling air with virion-containing respiratory droplets is described by extending the Wells–Riley model.
Cite:
Zhdanov V.P.
Stochastic Fluctuation-Driven Escape from Extinction: Basics and Application to Virology
Chemical Physics Letters. 2025. V.876. 142168 :1-5. DOI: 10.1016/j.cplett.2025.142168 Scopus
Stochastic Fluctuation-Driven Escape from Extinction: Basics and Application to Virology
Chemical Physics Letters. 2025. V.876. 142168 :1-5. DOI: 10.1016/j.cplett.2025.142168 Scopus
Dates:
| Submitted: | Jan 22, 2025 |
| Accepted: | May 19, 2025 |
| Published online: | Jun 5, 2025 |
| Published print: | Oct 1, 2025 |
Identifiers:
| Scopus: | 2-s2.0-105008105345 |
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