Sciact
  • EN
  • RU

Global Diffusion Limitations During the Initial Phase of the Formation of a Protein Corona Around Nanoparticles Краткое сообщение

Журнал Journal of Biological Physics
ISSN: 0092-0606 , E-ISSN: 1573-0689
Вых. Данные Год: 2019, Том: 45, Номер: 2, Страницы: 173–181 Страниц : 9 DOI: 10.1007/s10867-019-09522-8
Ключевые слова Nanoparticles Protein corona Diffusion limitations Injection
Авторы Zhdanov Vladimir P. 1,2
Организации
1 Section of Biological Physics, Department of Physics, Chalmers University of Technology, Goteborg, Sweden
2 Boreskov Institute of Catalysis, Russian Academy of Sciences, Novosibirsk, Russia

Реферат: Herein, I illustrate analytically how the global diffusion limitations can influence the first phase of the protein-corona formation at nanoparticles under conditions of intravascular injection. In particular, the concentrations of proteins near the boundaries of the injection region are shown to be comparable with those far from the region. In contrast, the concentrations of proteins inside the injection region may be dramatically smaller than those outside, and the ratio of these two concentrations for proteins of different size may be much higher, by a few orders of magnitude, for smaller proteins. These differences in the spatial distribution of proteins are expected to play a key role in the Vroman effect at the onset of the protein-corona formation.
Библиографическая ссылка: Zhdanov V.P.
Global Diffusion Limitations During the Initial Phase of the Formation of a Protein Corona Around Nanoparticles
Journal of Biological Physics. 2019. V.45. N2. P.173–181. DOI: 10.1007/s10867-019-09522-8 WOS Scopus РИНЦ CAPlus PMID OpenAlex
Файлы: Полный текст от издателя
Даты:
Поступила в редакцию: 22 авг. 2018 г.
Принята к публикации: 20 февр. 2019 г.
Опубликована online: 20 мар. 2019 г.
Опубликована в печати: 1 июн. 2019 г.
Идентификаторы БД:
Web of science: WOS:000470336300004
Scopus: 2-s2.0-85063155355
РИНЦ: 38672578
Chemical Abstracts: 2020:537127
PMID (PubMed): 30895408
OpenAlex: W2924999656
Цитирование в БД:
БД Цитирований
Scopus 1
Web of science 1
РИНЦ 1
OpenAlex 2
Альметрики: