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Kinetic Aspects of the Interplay of Cancer and the Immune System Научная публикация

Сборник The Physics of Cancer: Research Advances
Монография, World Scientific Publishing Co.. 2020. 280 c. ISBN 9789811223488. Scopus
Вых. Данные Год: 2020, Страницы: 229-242 Страниц : 14 DOI: 10.1142/9789811223495_0011
Ключевые слова Cancer; immune system; initiation; lifetime risk; tumor growth
Авторы Zhdanov Vladimir P. 1,2
Организации
1 Section of Biological Physics, Department of Physics, Chalmers University of Technology, Göteborg, Sweden
2 Boreskov Institute of Catalysis, Russian Academy of Sciences, Novosibirsk, Russian Federation

Реферат: The understanding of the interplay between cancer and the immune system is still limited. Herein, I focus on two aspects of this interplay. First, I propose a kinetic model describing the likely role of the immune system in the lifetime risk of cancer at the level of the whole human population. For each tissue, the risk is predicted to be influenced by the heterogeneity of the population and to depend exponentially on time. The expression for the risk does not, however, depend explicitly on the total number of divisions of the corresponding stem cells. For this reason, the correlation with the latter number can only be indirect. Second, using another kinetic framework, I describe how the growth of a few tumors can depend on their interaction via the immune system. The analysis shows that depending on specific details, the tumors of different sizes tend either to reach the same size or remain to be of different sizes.
Библиографическая ссылка: Zhdanov V.P.
Kinetic Aspects of the Interplay of Cancer and the Immune System
Глава монографии The Physics of Cancer: Research Advances. – World Scientific Publishing Co.., 2020. – C.229-242. – ISBN 9789811223488. DOI: 10.1142/9789811223495_0011 Scopus РИНЦ OpenAlex
Даты:
Опубликована в печати: 1 дек. 2020 г.
Опубликована online: 16 дек. 2020 г.
Идентификаторы БД:
Scopus: 2-s2.0-85109707910
РИНЦ: 46898869
OpenAlex: W3190927132
Цитирование в БД:
БД Цитирований
Scopus 1
Альметрики: