Abstract: The understanding of the interplay between cancer and the immune system is still limited. Herein, I focus on two aspects of this interplay. First, I propose a kinetic model describing the likely role of the immune system in the lifetime risk of cancer at the level of the whole human population. For each tissue, the risk is predicted to be influenced by the heterogeneity of the population and to depend exponentially on time. The expression for the risk does not, however, depend explicitly on the total number of divisions of the corresponding stem cells. For this reason, the correlation with the latter number can only be indirect. Second, using another kinetic framework, I describe how the growth of a few tumors can depend on their interaction via the immune system. The analysis shows that depending on specific details, the tumors of different sizes tend either to reach the same size or remain to be of different sizes.

Cite: Zhdanov V.P.
Kinetic Aspects of the Interplay of Cancer and the Immune System
Monography chapter The Physics of Cancer: Research Advances. – World Scientific Publishing Co.., 2020. – C.229-242. – ISBN 9789811223488. DOI: 10.1142/9789811223495_0011 Scopus РИНЦ OpenAlex

Dates:

Published print:	Dec 1, 2020
Published online:	Dec 16, 2020

Identifiers:

Scopus:	2-s2.0-85109707910
Elibrary:	46898869
OpenAlex:	W3190927132

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DB	Citing
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