Multi-Walled Carbon Nanotubes Increase Anxiety Levels in Rats and Reduce Exploratory Activity in the Open Field Test | Sciact - CRIS-система Института катализа

Multi-Walled Carbon Nanotubes Increase Anxiety Levels in Rats and Reduce Exploratory Activity in the Open Field Test Научная публикация

Журнал

Doklady Biological Sciences
ISSN: 0012-4966 , E-ISSN: 1608-3105

Вых. Данные

Год: 2015, Том: 464, Номер: 1, Страницы: 223-225 Страниц : 3 DOI: 10.1134/S0012496615050026

Ключевые слова

Multi Wall Carbon Nanotubes; Anxiety Level; Open Field Test; Exploratory Activity

Авторы

Sayapina N.V. ^1,4 , Batalova T.A. ^1,4 , Chaika V.V. ¹ , Kuznetsov V.L. ² , Sergievich A.A. ¹ , Kolosov V.P. ³ , Perelʹman Yu.M. ¹ , Golokhvast K.S. ¹

Организации

1	Far East Federal University, Vladivostok, 690001 Russia
2	Boreskov Institute of Catalysis, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090 Russia
3	Far East Scientific Center for the Physiology and Pathology of Respiration, Blagoveshchensk, 675000 Russia
4	Amur State Medical Academy, Blagoveshchensk, 675000, Russia

Информация о финансировании (2)

1	Федеральное агентство научных организаций России	V.45.3.5.
2	Дальневосточный федеральный университет	13-06-0318

The results of the first study on the effects of multi-walled carbon nanotubes (MWNTs) on the exploratory activity and the emotional state in laboratory rats assessed by the open field test are reported. During three or ten days, rats received 8–10 nm MWNTs added to their food at a dose of 500 mg/kg. It was demonstrated that, in the group of rats which were fed with MWNTs, the integrated anxiety level index began to increase as early as the third day of the experiment; on the tenth day, it appeared to be twice increased. It was also demonstrated that MWNTs decreased the integrated exploratory activity index nearly twofold on the third day and nearly fourfold on the tenth day.

Sayapina N.V. , Batalova T.A. , Chaika V.V. , Kuznetsov V.L. , Sergievich A.A. , Kolosov V.P. , Perelʹman Y.M. , Golokhvast K.S.
Multi-Walled Carbon Nanotubes Increase Anxiety Levels in Rats and Reduce Exploratory Activity in the Open Field Test
Doklady Biological Sciences. 2015. V.464. N1. P.223-225. DOI: 10.1134/S0012496615050026 Scopus РИНЦ CAPlus PMID OpenAlex

Саяпина Н.В. , Баталова Т.А. , Чайка В.В. , Кузнецов В.Л. , Сергиевич А.А. , Колосов В.П. , Перельман Ю.М. , Голохваст К.С.
Многослойные углеродные нанотрубки увеличивают тревожность крыс и снижают их исследовательскую активность в тесте “открытое поле”
Доклады Академии наук. 2015. Т.464. №1. С.115-117. DOI: 10.7868/S0869565215250283 РИНЦ OpenAlex

Поступила в редакцию:	10 февр. 2015 г.
Опубликована в печати:	1 сент. 2015 г.
Опубликована online:	4 нояб. 2015 г.

Scopus:	2-s2.0-84946014271
РИНЦ:	24968130
Chemical Abstracts:	PubMedID:26530062
PMID (PubMed):	26530062
OpenAlex:	W2296839929

БД	Цитирований
Scopus	9
РИНЦ	10
OpenAlex	9