Multi-Walled Carbon Nanotubes Increase Anxiety Levels in Rats and Reduce Exploratory Activity in the Open Field Test Full article
| Journal |
Doklady Biological Sciences
ISSN: 0012-4966 , E-ISSN: 1608-3105 |
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| Output data | Year: 2015, Volume: 464, Number: 1, Pages: 223-225 Pages count : 3 DOI: 10.1134/S0012496615050026 | ||||||||
| Tags | Multi Wall Carbon Nanotubes; Anxiety Level; Open Field Test; Exploratory Activity | ||||||||
| Authors |
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| Affiliations |
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Funding (2)
| 1 | Federal Agency for Scientific Organizations | V.45.3.5. |
| 2 | Far Eastern Federal University | 13-06-0318 |
Abstract:
The results of the first study on the effects of multi-walled carbon nanotubes (MWNTs) on the exploratory activity and the emotional state in laboratory rats assessed by the open field test are reported. During three or ten days, rats received 8–10 nm MWNTs added to their food at a dose of 500 mg/kg. It was demonstrated that, in the group of rats which were fed with MWNTs, the integrated anxiety level index began to increase as early as the third day of the experiment; on the tenth day, it appeared to be twice increased. It was also demonstrated that MWNTs decreased the integrated exploratory activity index nearly twofold on the third day and nearly fourfold on the tenth day.
Cite:
Sayapina N.V.
, Batalova T.A.
, Chaika V.V.
, Kuznetsov V.L.
, Sergievich A.A.
, Kolosov V.P.
, Perelʹman Y.M.
, Golokhvast K.S.
Multi-Walled Carbon Nanotubes Increase Anxiety Levels in Rats and Reduce Exploratory Activity in the Open Field Test
Doklady Biological Sciences. 2015. V.464. N1. P.223-225. DOI: 10.1134/S0012496615050026 Scopus РИНЦ AN PMID OpenAlex
Multi-Walled Carbon Nanotubes Increase Anxiety Levels in Rats and Reduce Exploratory Activity in the Open Field Test
Doklady Biological Sciences. 2015. V.464. N1. P.223-225. DOI: 10.1134/S0012496615050026 Scopus РИНЦ AN PMID OpenAlex
Original:
Саяпина Н.В.
, Баталова Т.А.
, Чайка В.В.
, Кузнецов В.Л.
, Сергиевич А.А.
, Колосов В.П.
, Перельман Ю.М.
, Голохваст К.С.
Многослойные углеродные нанотрубки увеличивают тревожность крыс и снижают их исследовательскую активность в тесте “открытое поле”
Доклады Академии наук. 2015. Т.464. №1. С.115-117. DOI: 10.7868/S0869565215250283 РИНЦ OpenAlex
Многослойные углеродные нанотрубки увеличивают тревожность крыс и снижают их исследовательскую активность в тесте “открытое поле”
Доклады Академии наук. 2015. Т.464. №1. С.115-117. DOI: 10.7868/S0869565215250283 РИНЦ OpenAlex
Dates:
| Submitted: | Feb 10, 2015 |
| Published print: | Sep 1, 2015 |
| Published online: | Nov 4, 2015 |
Identifiers:
| Scopus: | 2-s2.0-84946014271 |
| Elibrary: | 24968130 |
| Chemical Abstracts: | PubMedID:26530062 |
| PMID: | 26530062 |
| OpenAlex: | W2296839929 |