A Generic 3D Kinetic Model of Gene Expression Обзор
Журнал |
Central European Journal of Physics
ISSN: 1895-1082 , E-ISSN: 1644-3608 |
||||
---|---|---|---|---|---|
Вых. Данные | Год: 2012, Том: 10, Номер: 2, Страницы: 533-537 Страниц : 5 DOI: 10.2478/s11534-012-0011-5 | ||||
Ключевые слова | gene transcription, mRNA and protein diffusion and degradation, mRNA synthesis, mRNA translation, subcellular processes | ||||
Авторы |
|
||||
Организации |
|
Реферат:
Recent experiments show that mRNAs and proteins can be localized both in prokaryotic and eukaryotic cells. To describe such situations, I present a 3D mean-field kinetic model aimed primarily at gene expression in prokaryotic cells, including the formation of mRNA, its translation into protein, and slow diffusion of these species. Under steady-state conditions, the mRNA and protein spatial distribution is described by simple exponential functions. The protein concentration near the gene transcribed into mRNA is shown to depend on the protein and mRNA diffusion coefficients and degradation rate constants.
Библиографическая ссылка:
Zhdanov V.P.
A Generic 3D Kinetic Model of Gene Expression
Central European Journal of Physics. 2012. V.10. N2. P.533-537. DOI: 10.2478/s11534-012-0011-5 WOS Scopus РИНЦ
A Generic 3D Kinetic Model of Gene Expression
Central European Journal of Physics. 2012. V.10. N2. P.533-537. DOI: 10.2478/s11534-012-0011-5 WOS Scopus РИНЦ
Даты:
Поступила в редакцию: | 21 дек. 2011 г. |
Принята к публикации: | 21 янв. 2012 г. |
Опубликована online: | 31 мар. 2012 г. |
Опубликована в печати: | 1 апр. 2012 г. |
Идентификаторы БД:
Web of science | WOS:000302285700018 |
Scopus | 2-s2.0-84859213899 |
РИНЦ | 17981623 |
Chemical Abstracts | 2012:468153 |
Chemical Abstracts (print) | 158:67196 |
OpenAlex | W2056661723 |