Direct Selective Azidation of C(sp3)−H Groups Обзор
| Журнал |
Tetrahedron Chem
ISSN: 2666-951X |
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| Вых. Данные | Год: 2024, Том: 12, Номер статьи : 100114, Страниц : 21 DOI: 10.1016/j.tchem.2024.100114 | ||||
| Ключевые слова | azidation, C−H activation; homogeneous catalysis; late-stage functionalization; mechanism | ||||
| Авторы |
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| Организации |
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Информация о финансировании (1)
| 1 | Министерство науки и высшего образования Российской Федерации (с 15 мая 2018) | FWUR-2024-0032 |
Реферат:
Organic azides are convenient and versatile intermediates for the synthesis of various nitrogen-containing scaffolds, including biologically active compounds, approved drugs, functional materials, etc. Designing general approaches to deliberately chemo-, regio-, and steroselective synthesis of aliphatic azides is an urgent task of synthetic chemistry. Particularly challenging is direct azidation of non-activated C(sp3)−H groups, capable of providing ready access to remote and late-stage functionalization of complex targets without need for re-designing existing multistep synthetic procedures. This contribution surveys the existing C(sp3)−H azidation approaches, including catalytic and enzyme-mediated ones, with major focus on the coordination chemistry aspects and synthetic perspective of these transformations. Essential mechanistic details are briefly discussed.
Библиографическая ссылка:
Antonov A.A.
, Bryliakov K.P.
Direct Selective Azidation of C(sp3)−H Groups
Tetrahedron Chem. 2024. V.12. 100114 :1-21. DOI: 10.1016/j.tchem.2024.100114 Scopus CAPlus OpenAlex
Direct Selective Azidation of C(sp3)−H Groups
Tetrahedron Chem. 2024. V.12. 100114 :1-21. DOI: 10.1016/j.tchem.2024.100114 Scopus CAPlus OpenAlex
Даты:
| Поступила в редакцию: | 11 окт. 2024 г. |
| Принята к публикации: | 24 нояб. 2024 г. |
| Опубликована online: | 26 нояб. 2024 г. |
| Опубликована в печати: | 1 дек. 2024 г. |
Идентификаторы БД:
| Scopus: | 2-s2.0-85210292039 |
| Chemical Abstracts: | 2024:2656863 |
| OpenAlex: | W4404725856 |
Цитирование в БД:
Пока нет цитирований