Transient Stochastic Bistable Kinetics of Gene Transcription During the Cellular Growth Научная публикация
Журнал |
Chemical Physics Letters
ISSN: 0009-2614 , E-ISSN: 1873-4448 |
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Вых. Данные | Год: 2006, Том: 424, Номер: 4-6, Страницы: 394-398 Страниц : 5 DOI: 10.1016/j.cplett.2006.05.024 | ||||
Ключевые слова | Genes; Growth kinetics; Monte Carlo methods; Proteins; RNA | ||||
Авторы |
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Организации |
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Информация о финансировании (3)
1 | Swedish Research Council | |
2 | Stiftelsen för strategisk forskning | |
3 | European Commission | 505868 FP6-2002-NMP-1 STREP NANOCUES |
Реферат:
The feedback between mRNA and regulatory-protein production may result in bistability of gene transcription. If the mRNA and/or protein number are low, one can observe transcriptional ‘bursts’ in this case provided that the intracellular conditions are steady. Our Monte Carlo simulations show that for biologically reasonable kinetic parameters this effect may easily disappear if the transcription occurs during the cellular growth and division.
Библиографическая ссылка:
Zhdanov V.P.
Transient Stochastic Bistable Kinetics of Gene Transcription During the Cellular Growth
Chemical Physics Letters. 2006. V.424. N4-6. P.394-398. DOI: 10.1016/j.cplett.2006.05.024 WOS Scopus РИНЦ
Transient Stochastic Bistable Kinetics of Gene Transcription During the Cellular Growth
Chemical Physics Letters. 2006. V.424. N4-6. P.394-398. DOI: 10.1016/j.cplett.2006.05.024 WOS Scopus РИНЦ
Даты:
Поступила в редакцию: | 6 янв. 2006 г. |
Опубликована online: | 12 мая 2006 г. |
Опубликована в печати: | 24 июн. 2006 г. |
Идентификаторы БД:
Web of science | WOS:000238734200031 |
Scopus | 2-s2.0-33744907520 |
РИНЦ | 13511630 |
Chemical Abstracts | 2006:565891 |
Chemical Abstracts (print) | 145:181772 |
OpenAlex | W1967525295 |